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KMID : 0371319920420020199
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Journal of the Korean Surgical Society
1992 Volume.42 No. 2 p.199 ~ p.205
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Clinical Trial with Intraperitoneal Hyperthermic Perfusion for Intreaabdominal Cancer with Peritoneal Metastasis
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Abstract
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Intraperitioneal hyperthermic perfusion(IPHP) and chemotherpy has been tried after surgical treatment for 8 patients with advanced intraabdominal cancer in Seould Red Cross Hospital from early in 1990. There were two patients with peritoneal
recurrence
and metastasis, who have been in good health for a long time after IPHP combined with surgery.
Two 86-year-old and 65-year-old women were treated for recurrent colon cancer and cystadenocarcinoma by surgery and by thermal infusion and chemotherapy with a machine designed specifically for the treatment of cancers of serosal surface. After
completion of surgery, the patient's peritioneal cavity was instilled with 3 liters of 5% lactated Ringer's solution. They were then attached to hyperthermic perfusion system which elevated the temperature by warming to 44℃ and recirculated the
effusion solution with mitomycin(10 microgram per ml).
The patient's postoperatvie courses were uneventful except for pneumonia & exacervation of athmatic attack in the case of cystadenocarcinoma. These results show that IPHP using mitomycin(MMC) combined with surgery is a sate, reliable treatment
for
patients with peritoneal implantation of intrabdominal cancers.
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KEYWORD
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